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This weakens the immune system and allows opportunistic infections. CDC poster from 1989 highlighting the threat of AIDS associated with drug use. Due to their nonspecific character, these symptoms are not often recognized as signs of HIV infection. Main articles: HIV and pregnancy and HIV and breastfeeding. Unknown: if insufficient information is available to make any of the above classifications. Unsafe medical injections play a significant role in HIV spread in sub-Saharan Africa. Scanning electron micrograph of HIV-1, colored green, budding from a cultured lymphocyte. AIDS Clinic, McLeod Ganj, Himachal Pradesh, India, 2010. T cells are essential to the immune response and without them, the body cannot fight infections or kill cancerous cells.
Stage II: Mild symptoms which may include minor mucocutaneous manifestations and recurrent upper respiratory tract infections. The lower infectivity of HIV-2 as compared with HIV-1 implies that fewer people exposed to HIV-2 will be infected per exposure. Stage 0: the time between a negative or indeterminate HIV test followed less than 180 days by a positive test. HIV-1 is the virus that was originally discovered (and initially referred to also as LAV or HTLV-III). Even cases that do get seen by a family doctor or a hospital are often misdiagnosed as one of the many common infectious diseases with overlapping symptoms. Two types of HIV have been characterized: HIV-1 and HIV-2. After the virus enters the body there is a period of rapid viral replication, leading to an abundance of virus in the peripheral blood. Upon entry into the target cell, the viral RNA genome is converted (reverse transcribed) into double-stranded DNA by a virally encoded reverse transcriptase that is transported along with the viral genome in the virus particle.
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